Japan's Nikkei 225 Average climbed 120.32 points or 0.79 percent to 15,259.28 whereas Singapore's Straits Times fell 11.74 points or 0.36 percent to 3,224.76.
Asian equities were mixed on the last trading day of the week as concerns over Ebola and China offset gains on Wall Street.
A doctor in New York tested positive for the Ebola virus, the New York Times reported early on Friday, after returning from West Africa last week. Speaking at a press conference, New York Mayor de Blasio said officials believe "very few" people had contact with the doctor since his return. Markets reacted quickly to the news, with the Japanese yen strengthening 0.3 percent against the greenback and Dow futures dropping over 70 points before paring losses.
Meanwhile, attention in Asia was on China where official data showed new home prices falling 1.3 percent on year in September, the first annual drop in nearly two years. The report heightened concerns over the country's property market, which many experts say poses the single biggest risk to the economy.
US stocks surged on Thursday, with all three major indices climbing over 1 percent each, following strong third-quarter results from Caterpillar, 3M and General Motors. Meanwhile, data on Thursday showing the flash composite purchasing managers index (PMI) for the euro zone rising to 52.2 in October, from 52 in September, helped to ease some of the global growth concerns that recently plagued markets.
China's Shanghai Composite was up 6.47 points or 0.28 percent at 2,308.88 while Hong Kong's Hang Seng declined 33.10 points or 0.14 percent to 23,300.08.
Japan's Nikkei 225 Average climbed 120.32 points or 0.79 percent to 15,259.28 whereas Singapore's Straits Times fell 11.74 points or 0.36 percent to 3,224.76.
South Korea's Seoul Composite declined 10 points or 0.52 percent to 1,921.65 and Taiwan Weighted lost 85.38 points or 0.98 percent to 8,645.69.
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